I'm using GoToMyPC for Windows 10 and am running into two issues.
1. I have two monitors of different sizes. When I go into full screen mode (both remote monitors on both of my home monitos), part of the larger monitor ends up on the same screen as the smaller one. Neither scales to the full size of my monitors at home.
2. When my cursor is on my second monitor (full screen or otherwise) it reads the mouse as being in the wrong location. It is consistently clicks an inch up and a few inches to the left of where the cursor is shown.